Physical Examination 
There are no findings specific only to liver cancer on physical examination. Findings may include the following, all of which may have other explanations:
• Fever.
• Enlarged liver and spleen .
• Enlarged, hard lymph nodes . 
• Swelling of the abdomen from fluid (ascites).
• Jaundice (the skin turning yellow). 
• Swelling of the legs (edema).

Blood and Other Tests 
• A complete blood count may be normal or may show a decrease (anemia) or increase in red blood cells .
• Routine liver function studies—blood tests measuring serum bilirubin and liver enzymes—may be abnormal,
  but can be entirely normal even in advanced stages of primary liver cancer.
• Prothrombin Time and Partial Thromboplastin Time (PT and PTT) tests of clotting—usually done if a liver
  problem is suspected—may be abnormal.